There's a whole bunch of topics I just "Nope!" out of.

It's obvious they are complex, and, frankly, my interest in them is not enough to invest the time to even get to a basic understanding.

So, my canned answer is:

"It's complex, and I don't feel I know enough to have an opinion about it"

If it's something interesting, I might add on "What do you think about it?"

If it's not interesting I might throw on "And I'm not interested enough in even having an opinion. Thank you and goodbye"

That last part goes well with telecallers 🤣