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Researchers from Pritzker Molecular Engineering, under the guidance of Prof. Jeffrey Hubbell, demonstrated that their compound can eliminate the autoimmune response linked to multiple sclerosis. Researchers at the University of Chicago's Pritzker School of Molecular Engineering (PME) have developed

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[-] holycrap@lemm.ee 208 points 1 year ago

I've been following cures like this for years. There are three candidates in phase 2 trials right now that appear to work, they're mostly figuring out the doses needed and there's a big question on how long they last. Hopefully permanent but we don't know for sure.

Diabetics have just been so beaten down by this whole thing. I was told the cure was 10 years away 40 years ago. Even if the technology described here works we could be another 15 years before we see it. Researchers said it could be here as soon as 5 years, which is true if unrealistically optimistic. I believe the cure is coming but I'm not holding my breath until I'm actually in front of a doctor about to receive the cure whatever it happens to be.

[-] ramenshaman@lemmy.world 7 points 1 year ago

What are the 3 candidates you mentioned?

[-] holycrap@lemm.ee 9 points 1 year ago

I'll come back in a few hours when I'm on my computer and give you the list. I'm sure others will be interested in it as well.

[-] MajesticSloth@lemmy.world 2 points 1 year ago

I asked for a bit more info as well before I saw this response. Thanks.

[-] holycrap@lemm.ee 3 points 1 year ago

I posted more information above in this comment: https://lemm.ee/comment/3624282

TAK-101 is a celiac variant of a (currently paused) MS vaccine. I linked a video on that in my other post that may interest you. The video predates the decision to focus on just one disease. Basically the first iteration of their technology wasn't effective, but based on the theory that if it works on one autoimmune disease it should work on all of them, they've switched their focus to celiac because it's easier to test the efficacy. Just measure the amount of IL-2 during a gluten exposure. Also it's cheaper to run one trial than the 5 they had before for various diseases.

The good news is progress is being made on this. But don't expect it any time soon until you can actually book an appointment to get the procedure.

[-] MajesticSloth@lemmy.world 1 points 1 year ago* (last edited 1 year ago)

Thank you. I appreciate you taking the time to respond with more info.

I wasn't expecting much so no worries and not expecting anything soon. I've seen these things for a couple decades now. But this one is interesting. So again thank you.

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this post was submitted on 16 Sep 2023
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