"And I, too, felt ready to start life all over again. It was as if that great rush of anger had washed me clean, emptied me of hope, and, gazing up at the dark sky spangled with its signs and stars, for the first time, the first, I laid my heart open to the benign indifference of the universe.” this quote by Camus in "The Stranger" always get me. Points out the absurdism of searching for a meaning in this vast, complex and more importantly indifferent universe.

Of course, Nietzsche felt different. He thought we still had an obligation to do great.

To me personally, taoism seems to provide a happy middle ground. Do what you can, try what you want. In the end success or failure brings some pros and some cons. Life is all about navigating the water current. Sometimes, you take control and other times you let the water carry you. It is all about knowing when to do either.