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Framework’s first desktop is a strange—but unique—mini ITX gaming PC
(arstechnica.com)
This is a most excellent place for technology news and articles.
It's already fourth tier after L1, L2, L3 caches.
Maybe something like optane will make a comeback. Having 16gb of soldered RAM and 500gb of relatively slow, but inexpensive optane RAM would be great.
DRAM is so cheap and ubiquitous that they will probably keep using that, barring any massive breakthroughs. The "persistence after power-off" is nice to have, but not strictly needed.