I did accutane about 25 years ago now.

The only thing I really remember being an issue was the random nose bleeds. Keep a spare shirt nearby and something to stop up your nose when you can. I was super super dry for a while when I was on it but my skin eventually went to a 'normal' level after treatment ended. I still have dryness on my forehead so I have to use a moisturizer every morning. My acne virtually disappeared. I get the occasionaly white head but we're talking maybe one every couple of months.