I think the current mind state of the group is more important than sobriety or gender (though both of those probably play a role). At least for me, I can have a hard time immediately switching gears socially, that coupled with the shock of having someone start ranting about something I had no idea of, would be hard to be a total role model. I'd probably end up doing something similar to OOP, I definitely wouldn't awkwardly leave because I'd feel too bad, I'd probably ask if they'd talked to anyone or seen a doctor but if the other guy was also super drunk and ranting I don't know how long I'd be able to stick around