The amount of CPU time compiling code is usually negligible compared to CPU time at runtime. Your comparison only really works if you are comparing against something like Rust, where less bugs are introduced due to certain guarantees by the language.

Regarding "language constructs" it really depends on what you mean. For example using numpy in python is kind of cheating because numpy is implemented in C. However using something like the algorithm libraries in Rust woulf be considered fair game since they are likely written in Rust itself.