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In the middle of the print change the flow modifier to 0%.
That will turn off the extruder while leaving everything else as-is.
I suspect it's the X or Z bearings.
Please don't sand anything. If your problem is wear, adding wear will not help.
Another thing you can do is move the print head up, and while not printing anything just extrude 100mm of filament. Then you will only hear the extruder.
The only thing in the extruder that I would expect to make a noise like that would be if it's a geared extruder with seriously abused gears that are slipping. But then you'd see extrusion problems.
In general, the extrusion motor should be way to slow to create such high-frequency noises, unless your motor control is seriously wrong setup.