Sure, I was doing genome compression for tree comparison in the late 90s for in memory analysis and the speed up was very significant. The idea of a universal specification format and a universal decoder is IMO bloody brilliant, hell with a bit of training I'd be unsurprised if you could point a LLM at a format and get 90+% of the way there with the specification for most simple-ish formats, and probably have a manual crack at simple relational databases. Potentially you could also switch out huffman for encryption for efficient zero-knowledge proofs as well.