A druid who got involved because they're the party's weed dealer.

Isn't that the plot of Dazed and Confused?

A werewolf who doesn't believe in the moon.

This would play out as an unintentional (or intentional) allegory for addiction, and the denial that masks it. The party would very likely form an intervention of some sort. I mean, they'd have to. After the third werewolf attack or so, it starts to become a real problem.