Yes and no. We often differentiate between "comics" and "actors" as people who belong to different disciplines of entertainment. Robin Williams and Jim Carrey got their starts in stand-up, and Bill Hader as an improv sketch comic. It's pretty commonplace for notable comics to transition into comedic acting on screen, but that's basically the type of production they get typecast into from that point on.

So when much of the industry places all this emphasis on having backgrounds in stage, working up through the indie circuit, or having some sort of Hollywood pedigree, it's notable when a comedic actor manages to break free of the typecast and thrive.