The Japan Multi-Institutional Collaborative Cohort Study investigated the relationship between dietary carbohydrate and fat intakes and the risk of mortality in the Japanese population[1]. The study found that:

• An unfavorable association with mortality was observed for low-carbohydrate intake in men and for high-carbohydrate intake in women[1].

• High fat intake could be associated with a lower mortality risk in women among Japanese adults with a relatively high carbohydrate intake[2].

• The Prospective Urban Rural Epidemiology study demonstrated that high-carbohydrate and low-fat intakes were associated with an increase in risk for mortality[3].

• Extreme dietary habits involving carbohydrates and fats affect life expectancy[4].

• Men with high fat intake had a higher risk for cancer mortality; the multivariable-adjusted HR (95% CI) for ≥35% was 1.79 (1.11-2.90) compared with 20%-<25% [5].

the study suggests that extreme dietary habits, particularly those involving carbohydrates and fats, can affect life expectancy in the Japanese population. It is important to consider these findings when making dietary recommendations and promoting a balanced diet for optimal health.

Citations: [1] https://pubmed.ncbi.nlm.nih.gov/37271417/ [2] https://www.sciencedirect.com/science/article/abs/pii/S0022316623721986 [3] https://www.sciencedirect.com/science/article/pii/S0022316623721986 [4] https://omniaeducation.com/news/extreme-dietary-habits-for-carbohydrates-fats-affect-life-expectancy-findings-from-a-large-scale-cohort-study-in-japan/2452354/ [5] https://www.researchgate.net/publication/371268749_Dietary_carbohydrate_and_fat_intakes_and_risk_of_mortality_in_the_Japanese_population_the_Japan_Multi-Institutional_Collaborative_Cohort_Study [6] https://jn.nutrition.org/article/S0022-3166(23)72198-6/pdf