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Popular Sweetener Found in Protein Bars Tied to Stroke, Blood Clot Risk (gizmodo.com)
submitted 3 weeks ago by return2ozma@lemmy.world to c/fitness@lemmy.world
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It's sugar alcohol, erythritol.

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[-] illusionist@lemmy.zip 3 points 3 weeks ago* (last edited 3 weeks ago)

DeSouza noted that, although deeper clinical research would be needed, his lab’s findings could be deemed conservative given that only a single serving amount of erythritol was tested in their study, published in the Journal of Applied Physiology. Someone who routinely guzzles zero-sugar energy drinks or pounds multiple low-calorie protein bars in a single day, in other words, could possibly experience a more extreme version of these effects.

They tested a single dose?

If they prove erytrol to be toxic, why is it still legal? Maybe it's not so deadly as they write.

[-] Squirrelsdrivemenuts@lemmy.world 6 points 3 weeks ago

There are several caveats/nuances:

  1. They applied the dose (6mM, or 0.7g/L, which they say is equivalent to a one time 30 gram dose) directly to a monoculture of cells present in the brain vasculature and exposed them for 24 hours. I don't have time to look this up in detail but I imagine not all erythritol ends up in the brain and it should not last for 24 hours in the blood due to your metabolism. Other cells might also play a role in buffering the effect.
  2. Your body makes erythritol itself in response to stressors such as obesity. I did not see comparison of normal blood levels versus blood levels after consumption.
  3. Monocultures in the lab are always more stressed out and responsive to stressors than the cells in your body, so while they give indications of effect and pathways, they are really bad for estimating dose-response
[-] illusionist@lemmy.zip 0 points 3 weeks ago

Thank you a lot for elaborating on it. Sounds like they are just spreading FUD.

this post was submitted on 31 Mar 2026
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