Actually there's also the breaking of the psychological state of Flow, which is the mental state of total focus and maximum productivity, which takes about 15 minutes to get to.

Years ago when I had to work as a programmer from the Trading Floor of a major Investment Bank (think Fishmongers' Market but with Financial Assets) I bought some noise reduction earphones and have used those kind of things ever since as they really cut down on distractions and it mainly works.

It even cuts down on the "can you help me for a second" thing because other people actually have to get up and move to were you are to get your attention (as you can't hear them unless they shout), so the zero-effort choice of just calling you from their seat to help them isn't there anymore and one thingI learned pretty early in my career is that in the absence of a zero-effort help path through you for their problems, your colleagues will actually try to first solve their problems themselves and only come to you if they're really stuck, whilst if you're the least effort path to having their problems solve most will just default to breaking your focus and using your time to have their problem solved.