1452
Not to get too political but...
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https://www.scientificamerican.com/article/as-earth-warms-the-diseases-that-may-lie-within-permafrost-become-a-bigger-worry/
https://www.pbs.org/newshour/science/climate-change-will-result-in-new-viruses-and-risk-of-new-diseases-says-study
Diseases that may lie in permafrost give reason to worry. These articles are entirely speculative and openly alarmist in nature, I wouldn't trust them to sway your opinion if I were you.
There's never been a dormant disease that's been found and revived from permafrost that we have any reason to believe could infect human, let alone any explanation of how such a disease could make it into the human population just through the thawing of permafrost alone. It's not just that I don't think we have reason to worry, I actually think we have plenty of reason not to worry.