I remember rolling 20+ d6 in Shadow run to shoot at someone. Also evocation wizards in dnd 5e like to have a word.

Lastly as a GM I like to have 6 dice sets for one shots especially with new folks or at conventions. So I can hand out a set for everyone.

Also maybe I'm trying to justify owning like 12 or so dice sets. But they all fit in my large dice bag with compartments for each dice type. Also none of them are fancy dice. They are just easy to read high contrast single color dice. All of them.