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this post was submitted on 29 Nov 2023
675 points (97.6% liked)
Comic Strips
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Comic Strips is a community for those who love comic stories.
Rules
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π Be Nice!
- Treat others with respect and dignity. Friendly banter is okay, as long as it is mutual; keyword: friendly.
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ποΈ Community Standards
- Comics should be a full story, from start to finish, in one post.
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- Any comic that would qualify as raunchy, lewd, or otherwise draw unwanted attention by nosy coworkers, spouses, or family members should be tagged as NSFW.
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𧬠Keep it Real
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π½οΈ Credit Where Credit is Due
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β Correct: https://xkcd.com/386/
β Incorrect: https://xkcd.com/
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SΓ, por favor [Spanish/EspaΓ±ol]
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πΏ Moderation
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Banned Artists
The following artists are banned from the community.
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Note: This is not a rule, but a helpful suggestion.
When posting images, you should strive to add alt-text for screen readers to use to describe the image you're posting:
Another helpful thing to do is to provide a transcription of the text in your images, as well as brief descriptions of what's going on. (example)
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You're right it wasn't a very scholarly article, that article was just the first thing that pops up on a Google search meant for people who weren't familiar with Olestra, was mostly intended as a joke.
To take it more seriously though, a lot of those studies took place after a formulation change, so the later incarnations may have been better. It's also possible that some of the reports came from people consuming large amounts of it at once. The studies I saw that didn't show much difference all had a relatively small amount of chips ingested (see studies cited by article here https://www.acsh.org/news/1996/12/01/whats-the-story-olestra#3), for instance one of these studies was a double blind crossover with only 2 Oz of chips. I'm not aware of studies that would simulate downing a whole can of Pringles with Olestra at once. It was often included in snack foods that people don't always moderate themselves on. Many of these studies, like the one you cite, were run by the manufacturer so important to be skeptical of the methods. They apparently started to fortify it with fat soluble vitamins to address concerns it could exacerbate deficiencies of those vitamins (besides basic science which should logically suggest this would happen, there's evidence to back that up as well https://jn.nutrition.org/article/S0022-3166(23)01561-4/fulltext). The principle of every stool softener on the market now is that it's something your body cannot absorb that will remain in the gi tract, eat enough Olestra or anything like it and it'll have an impact on your stool consistency, just a matter of dosing. Animal studies also suggested it doesn't cause weight loss and may even lead to increased weight. In the end it stopped being sold in the US altogether, because why go to all that trouble for something that probably doesn't have any benefit.
It's tough though, common symptoms are common. Many side effects you see on medications or things like Olestra may not even have anything to do with the product and were just coincidence or nocebo effect.