So, the solution i use is relativly simple. I mainly use the Adguard Adblocker, as i see that as one of the best adblockers you can get. Since Twitch uses some weird methods to load ads, you normally see them on every Adblocker. Now, the Adguard Team came up with some additional addon called Adguard Extra. Dont really know what it does, but seems like it detects ads on another way. Both installed, you dont get any ads anymore on Twitch.

Both Extensions are of course open-source and can be viewed on GitHub. https://github.com/AdguardTeam/AdguardBrowserExtension https://github.com/AdguardTeam/AdGuardExtra

Download for Chrome: https://chromewebstore.google.com/detail/adguard-werbeblocker/bgnkhhnnamicmpeenaelnjfhikgbkllg https://chromewebstore.google.com/detail/adguard-extra/gkeojjjcdcopjkbelgbcpckplegclfeg

Download for Firefox: https://addons.mozilla.org/de/firefox/addon/adguard-adblocker/ https://agrd.io/adguard_extra_firefox_release (note: this extension is currently not in the firefox addon store, you download the file manually)