I have heard it runs on steam deck, but nothing about Mac yet.
The game engine was switched from Unity to Unreal Engine 5.
With Unreal Engine 5.2 it looks like Epic is bringing additional support for macOS, although there's still some work that needs to be done.
https://primagames.com/tips/what-engine-does-palworld-use-answered
https://www.unrealengine.com/en-US/tech-blog/unreal-engine-5-2-brings-native-support-for-apple-silicon-and-other-developments-for-macos
The game engine was switched from Unity to Unreal Engine 5.
With Unreal Engine 5.2 it looks like Epic is bringing additional support for macOS, although there's still some work that needs to be done.
https://primagames.com/tips/what-engine-does-palworld-use-answered
https://www.unrealengine.com/en-US/tech-blog/unreal-engine-5-2-brings-native-support-for-apple-silicon-and-other-developments-for-macos