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I know this is "just a joke" but I still think it's harmful. Depression may be brought on by being in a bad situation but it isn't simply unhappiness or dissatisfaction with being in that situation. Antidepressants don't make a person artificially happy or numb. If you are clinically depressed because your life sucks, antidepressants may give you the mental fortitude needed to change your circumstances. There are drugs that people do use to try to cope which just make things worse, but you won't get then from a psychiatrist. (You can get the most popular one at the grocery store.)
It's not cool to stigmatize mental illness.
This is not at all what my take away from that comic is. I guess it is somewhat open to interpretation, but I think it rather asks what the underlying societal dynamics are that cause people to develop depressions in the first place.
This was also my takeaway. The comic isn't making a value determination for medication in any form, but instead commenting that we as a society would rather address symptoms rather than address any root causes.