I'm a C++ dev, I have one checkout of the main repo and 3 worktrees. Switching branches can be expensive because of recompiles, so to do e.g. quick fixes I'll use worktree 1 where I typically don't even compile the code, just make the fix and push it to the CI system. Worktrees 2 and 3 I keep at older releases so I can immediately fire up development and one of those releases side by side and compare results as well as the code.

The cool thing about worktrees instead of multiple checkouts is that you only have one .git folder, so less disk space. But more importantly local branches (well everything actually) are shared, so you can create a local branch in the main checkout, and later come back to it in a worktree. You also don't need fetching/... in the worktrees, as they share the same .git folder.

Only thing that I found virtually impossible to work with is worktree + submodules.