Measure differences in what? We can't ask *c. elegans * about it's state of mind let alone consciousness. There are several issues here; a philosophical issue here about what you are modeling (e.g. mind, consciousness or something else), a biological issue with what physical parameters and states you need to capture to produce that model, and how you would propose to test the fidelity of that model against the original organism. The scope of these issues is well outside a reply chain in Lemmy.