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this post was submitted on 29 Jun 2023
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I sort of cringe (more of a nose wrinkle really) at OP's "it's known in some circles to be bad" You see beliefs and correlative evidence constantly misrepresented as proof and truth in food and medical science (reporting and discussion).
I get it. The body is a hugely complicated system, it's hard to figure these things out. What does even figuring them out mean with the amount of complicating factors of this affects that which affects this which causes this.
I'm open to the idea that lobbying and such means Aspartame (and other industrial food products) has really been pushed through.
It's also obviously been studied quite a bit and it's hard to believe all the studies saying it's safe at recommended levels are bunk or fraudulent.
This news was on another instance where the discussion included that the IARC carcinogen classifications do not take into account exposure/dosage. A whole bunch of things can be carcinogenic depending on exposure. Haven't we all read how the rats that got cancer from saccharine had epic doses? It was just magnitudes more than a human would consume.
If an observational study won't cut it (I see you, @xthedeerlordx, and appreciate your comment and explanation), how does one prove the causation? Don't you need randomized controlled trials which would be extremely onerous controlling for various factors and basically making the (ideally large number of) participants live in a lab for whatever amount of time the study takes to really prove causation? I'd genuinely like to know. It seems like for a lot of things correlation after correlation after correlation is the best we're going to get.