Yeah, tolerance and dosing with shrooms is kinda tricky (as in there's a trick to it, not that it's really difficult) if you're doing them with any regularity. I wouldn't be surprised if it's similar to that where you have to take quite a bit more to not only break the threshold to trip again but achieve the same level of trip, and your tolerance lessens with each day that passes.

I might be able to attest to that if I had been doing shrooms a little longer before I started strattera. Perhaps it's harder to achieve higher level trips, now that I think about it. But this is new information to me so it's something I'll have to keep an eye on. I happened to take .3g last night and got a bit more bang for my buck than expected. I also forgot to take my strattera yesterday. Coincidence? Maybe, maybe not. Low level trips are still valuable though imo.