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‘Right to Repair for Your Body’: The Rise of DIY, Pirated Medicine
(www.404media.co)
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It is easy to make if you have the know how and some equipment, also if it is already known what you need to make. For example, aspirin is known structurally (unless I am mistaken), so if you have the chemistry know-how and equipment, you can make your own.
However the tricky part is to get it as a safe medicine to take, that you do not have impurities that could be dangerous, toxic. You will need to be able to make quality and safety checks like that. Which I am not sure how easy that really is.
White willow bark and devil's claw root contain naturally occurring salicylic acid, similar to aspirin. Better, but it tastes funky.
ETA: https://www.mountsinai.org/health-library/herb/slippery-elm#:~:text=Slippery%20elm%20contains%20mucilage%2C%20a,throat%2C%20stomach%2C%20and%20intestines.
Nothing wrong with homemade medicine. Just know what you're doing. I've used many, on myself and now adult child. Grandparents on both sides taught me. Their's taught them. I've used comfrey to heal deep wounds on friendly strays.
Along the same line of pain management did you know that pretty much all the poppy seed (for ornamental flowers) you can buy at any garden store are opium poppies? You can grow them easily, then macerate the whole plant and extract in off the shelf alcohol and strain it for essentially laudanum which is great for a sleep aide or pain in low to moderate doses. Quite safe as well, obviously if you don't abuse it.