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The official support of Windows 7 has finally ended today!
(sh.itjust.works)
This is a most excellent place for technology news and articles.
Except ME was part of the DOS line, while XP extended Win2k which is NT.
But I take your point, just that Win2k was (largely) the end of MS producing DOS-based operating systems (with XP being the final nail in that coffin).
In business, once Win2k was out, we stopped deploying Win9x entirely. Before that, NT was problematic on some hardware and for some software/users. Win2k solved most of that.
Win2k and WinXP were not built on DOS. They were not DOS-based. They were NT-based. ME was the final nail in that coffin.