Well if you subject your guitar to humidity fluctuations, it may well crack. Many do. My guild had a crack when I bought it, and when I moved to colorado it developed another. I have another guitar that has survived lots of changes in humidity and severe dryness without cracking. Maybe the wood was cured better, or I just got lucky.
I keep my nice martin humidified to ~47% all the time. Maybe it would survive dryness, but I don't want to take the chance. When they dry out it changes the way they play, being humidified properly helps keep the action consistent as well as protecting it against cracks.