A mole of moles (the mammal) is fucking up the local environment.

A mole of moles (skin condition) is death by really weird cancer.

A mole of moles (structure separating bodies of water) is a perplexing strategy of coastline management.

A mole of moles (spies) is global instability.

A mole of mole (sauces) is a tasty, tasty feast.

A mole of Molé (surname) is a very French affair, hopefully some of them brought baguettes and fromage to share.

I had a chemistry question in high school about a mole of moles. Everyone got it wrong because Ms. Mulder wasn't a very good teacher, nor was she good at writing chemistry questions.

There really is an xkcd for everything.