There are no issues with InDesign (latest or earlier versions) when patched with the latest GenP.

If any problems existed, they would be documented in the Compatibility List and mentioned in the Announcements channel on GenP Stoat.

For reference, InDesign v21.0.2 works perfectly when patched with GenP v3.7.1, and there are no issues related to it closing immediately upon opening.

It's worth noting that I have been updating my own InDesign up to v21.0.2, repatching with GenP v3.7.1, all without any issues.

If this were a common problem caused by GenP, others would be reporting similar crashes, which they are not.

Therefore, the crash after patching may be due to specific system or environment factors rather than the patch itself.

InDesign crashing immediately on launch is usually caused by corrupted background Adobe processes, blocked components, or damaged preference files.

It can also happen if antivirus software is scanning or blocking InDesign during startup.

The process still in use issue can often be resolved by fully closing all Adobe processes in Task Manager and then restarting.

Resetting InDesign preferences, clearing its cache folders, and ensuring CC services are running properly can also fix sudden-close issues.

If the problem persists, performing a clean reinstall is recommended, as leftover or inconsistent files can trigger launch failures.