Multiple monitors pretty much just work. Wacom-type integration is just as immediate. I don't foresee any serious issues here, but do report back.

Works good on mine don't know about Wayland.

Only problem might come with resolution if the screen is a very unique size.

try it. let us know. from dude with 3 mismatched screens. sony huge screen thru sony strdn1080, and a 27 dell landscape and a dell 29 portrait. clustered to watch f1 with miltiviewer.

don't know about wayland, but kde works almost perfectly, even though there are some very minor bugs.

I used KDE with X11, an AMD card, and two different sized monitors for the longest time without any issues. It's pretty plug and play.

With Wayland I did try months ago and it just worked™, but I don't have a long experience with it.

Unfortunately, I've no direct experience with the touch integration.

I've been using Nvidia+Wayland+Gnome with two different monitors for a while now, and never had any problems with this setup. The X11 setup before that had some issues years ago, but worked fine for the last few years before switching to Wayland.

I also connect different external monitors to my Intel-based laptop fairly often, and it works 99.9% of the time.

Multi-monitor is really just plug and play nowadays.

If you stick with Wayland it will not be a problem. X will technically work but the touch screen input will likely be broken and the text will be blurry or to small.

I had small issues with Wayland so I switched to X but I think DP to HDMI and after that HDMI to VGA makes problems with anything.

I'm using 3 monitors (one laptop and 2 desktop) fine on Gnome 3 with Wayland and integrated graphics. Minimal extra steps that were all Gnome related with a vertical monitor, so may not be an issue in KDE.

No issues whatsoever. Recommend Wayland since you'll probably want fractional scaling