Yes, they are separate. If you are talking about the new profile manager and the "old" about:profiles one, they are separate sets of profiles and cannot see each other's profiles.

If I remember correctly, the about:profiles data is stored in folders, while the new manager uses an sqlite database.

Can you please share how you created the guide? I would like to make one myself.

https://www.netcup.com/en/domain/buy-register-domain

Based in Germany