Vampire: The Masquerade - Bloodlines has special lines that unlock according to your character build. Unlike a single Charisma skill, they're divided into skills like 'Intimidation', 'Seduction', 'Erudite', etc. Intimidate options appear in ALL CAPS HULK SPEAK, seductive options are in italic in handwriting, and Erudite appears in blue. If you lose your humanity and become too bestial, dialogue starts disappearing as you're too far gone to understand it and NPCs start being too scared to talk to you.