Yuzu (and Ryukahr) are not 1:1 emulators though, and they aren't attempting to. Attempting 1:1 emulation of the hardware is only feasible with very old hardware like the NES or whatever, where modern hardware doesn't have a problem simulating every detail of the CPU. Yuzu doesn't try to simulate the Tegra SoC that's in the Switch, I think it works by transpiling game code and hooking into system calls and whatnot, similar to what Proton does on Linux (only probably more complex).

If the Denuvo team studied how these emulators work well, it's probably very hard to effectively defeat Denuvo DRM in general (as opposed to on a per-game basis).