The most basic prompt I could write for this:

Panel 1:

Janeway riding a bike labeled “Voyager crew in the Delta Quadrant.”

Caption: “We’re stranded 70,000 light years from home, let’s be smart and careful.”

Panel 2:

Janeway happily jamming a stick into her own bike wheel.

Caption: “Break the Prime Directive, ally with dangerous aliens, get half the crew killed every other week.”

Panel 3:

Janeway lying on the ground, holding her leg, blaming others.

Caption: “The Delta Quadrant is so hostile! Why is it so hard to get home?!”