The problem with a lot of these papers is they use intermediate endpoints rather than actual hard end points. They're making the assumption that decreasing LDL is a good thing. That's an intermediate endpoint, nobody actually cares about their LDL, they care about their health span and lifespan.

Spoiler: LDL and Cholesterol in general is not a disease, it's poor metabolic health that is the actual cardiovascular problem.

I.e. https://doi.org/10.3390/metabo14010073 Oreo cookie treatment lowers LDL cholesterol more than high-intensity statin therapy in a lean mass hyper-responder on a ketogenic diet: a curious crossover experiment

This stunt paper illustrates how silly it is to focus on a intermediate metric. Oreos are not health food, I should hope that is obvious