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I usually take 20 mg adderall in the morning anytime from 8-9:30 am. The therapeutic effects for the 4 hours that it’s sold as lasting. The problem is that I have difficulty falling asleep 1-2 hours past my bed time.

And I’m going to have to start taking it in the afternoon. I’ve heard eating citrus helps counteract the effects. I’ve tried melatonin, which has helped to a degree

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[-] Sulvy@hexbear.net 5 points 3 days ago

This is only half right, vitamin C does increase the acidity of your stomach. And it is not the physical breakdown of the pill, but how the increased hydrogen ions (H+) bind with the amphetamine molecules and prevent them from crossing your lipophilic GI membranes.

[-] baahb@lemmy.dbzer0.com 3 points 3 days ago

Dope. I'm super not into chemistry, but I saw enough misconception to try and clean up before someone started trying to offset drugs with drugs.

So, lemme poke this a bit...

First, its basically any acid. But stronger means higher impact. Vitamin C is not the important chemical, but it does increase the effect cause its stronger than stomach acid?

Lipophilic... Fat loving... Okay so in the stomach the acid works to neutralize the adderol, but higher acidity means more ionization which makes it harder to absorb through your stomach or intestinal lining?

Are those assumptoons correct?

Still thiygh, once your body has metabolized the adderol into your blood stream, you gotta deal with it being in your blood stream.

[-] Sulvy@hexbear.net 2 points 3 days ago

Yeah it’s any acid, and I think the acidity actually comes more into play once the drug and the acid enter your small intestine as it’s hard to beat your own stomach acid.

Yeah that second part is right, I don’t really recall the mechanics of it well enough to explain but this gives a pretty good breakdown: https://www.merckmanuals.com/professional/clinical-pharmacology/pharmacokinetics/drug-absorption

this post was submitted on 20 Apr 2026
38 points (100.0% liked)

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