I don't agree with that dichotomy in a game like this. Certainly in the deeply simulationist roguelike I stan (cataclysm dark days ahead plug), that's appropriate, but this game is fundamentally silly and arcade style so I don't think the trouble has anything to do with realism. The solution I'd have personally in something like this is to eg. allow you to carry up to 6 weapons, 1 of each wearable type of item, and a certain amount of aid items in your "active" inventory, and then have everything else you loot automatically go to your ship inventory which is huge or infinite, but restricted in how you can access it (personally I'd still have ship inventories be finite, but enormous). Let perks increase your number of slots in a particular category, rather than increasing carry weight. Have resources and 'notes' go to the ship automatically as well, since it doesn't really have any impact on the game to be carrying these on your person. Plus, I'd do what modders have been doing for a while and make decorative junk items have no value or weight. Let me pick up as many blenders as I want, I'm just going to use them to decorate my juice bar and play house, who frigging cares.

I'd also remove vendor credit caps, but make the amount of cash you get from loot pretty trivial compared to what you get from missions, so it's just not that appealing to sell 15 cheap machineguns. And while I'm wishlisting, I'd love to be able to set up an auto-sell filter, eg. 'sell non-unique weapons below a particular dps'