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Netflix to open branded retail stores for some reason
(www.engadget.com)
This is a most excellent place for technology news and articles.
I mean the spaceships in star trek, star wars and firefly all have pretty different interiors. Of your idea is to draw in fans of specific shows you don't really want to have a "generic sci fi" setting.
Well, yeah you wouldn't be able to re-use everything but certain things like the building structure and cutlery, flooring, etc probably wouldn't have to be modified much. Some of the more expensive things to switch out.