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There's drugnerd whispers on the internet that DXM (microdosed) can block or attenuate the development of tolerance to various ligands, particularly amphetamine.

Any DrugNerdz here who can explain the valudity of this conjecture or expand on it in any helpful way

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[-] cheese_greater@lemmy.world 3 points 1 year ago* (last edited 1 year ago)

Dude, like what is the bottom line with your comments here? Trust me, I'm better than ever and I have zero intention of touching DXM for a very long time (legit had an issue with urinary retention one time that was beyond uncomfortable but I also just hate throwing up ever if I don't have to).

Thisnis purely out of curiosity about whether it can help attenuate general tolerance development for various substances (itself being taken at a microdosage level—not plateau territory, as I suspect you're implying). It is almost purely academic besides the plausibillity and ease of trying it out for anecdotal purposes.

[-] intensely_human@lemm.ee 0 points 1 year ago

Why do you think DXM might have this property?

I’ve not heard of this being a property of any substance or procedure.

this post was submitted on 21 Oct 2023
25 points (93.1% liked)

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