I feel like this would be a question best addressed where the online blind community hangs out (er... I don't actually know where that is), and there may be plenty of blind users here (?) but I also wouldn't be surprised to hear there are not. I certainly would tear my hair out if I had to work through comments audibly to try to work out what might be worth reading. But I don't know and I'm not trying to speak for blind people.

The one blind developer I knew was heavily into Emacs, which has historically had a speech interface and can operate very well purely text-based, that I think made it a good choice. His ability to be productive was awe inspiring. I don't know if anything else has taken over, but I expect if I lost my sight it might become my entire environment since I already know it. But I wouldn't be surprised (and hope) there are more suitable options for less technical users.