There's indeed knowledge like that. Like there's knowledge that, at the moment of understanding, overloads your brain. It's like your entire model of reality has become invalid, and it can cause physical pain as your brain burns out trying to recalculate everything you know in this new paradigm. Sometimes you go through days in a fog as your brain recovers, sometimes it can still hurt every time you think of it months later. The implications of certain understandings just start the process over all over again

Here's a particularly grounded and well supported example that's not transmissible enough to be an info hazard - everything is waves. There's no particles, just waves of energy that form stable patterns