The destruction part is nonsense, as there is much to be prevented, even still a world to be gained despite the horrors inflicted. As far as agitation within the U.S., it's true most of it has not had a direct material effect, despite mass protests forcing changes in rhetoric from the U.S. (empty, of course). "This" has not "run its course" until the Palestinian people have been eradicated--until then every American owes their life to the struggle, and afterwards still to all those oppressed by Western imperialism. If community agitation has not proven effective in rousing support for mass action, this is understandable considering the scourge of opportunism; providing whatever support is possible to groups actively engaged in the struggle (ex. Hamas, PFLP, Hezbollah) is the only option. This is difficult for multiple reasons (surveillance, barriers of access), and yet, this is the nature of what has to be done.