1419 was the first. Well, few of them did survived since that window wasn't terribly high, unfortunately for them city hall was surrounded by angry mob who finished them.

The one with angels was the Third Defenestration in 1618, this time everyone survived (also there were no clergy thrown out afaik) because while the window was higher, they fell on the pile of manure which were in fact the leftovers of their own earlier feasts thrown out the same route (this wasn't angelic enough for official history but the real version was passed too).