I use Restic + Resticprofile to back up everything and store it on my local HDD.

Then, I use Rclone to sync the local repository to Backblaze B2.

Here's my general setup:

/.config/restic/
├── logs
│   ├── statuses
│   │   ├── restic-status-20230202T020202.json
│   │   └── restic-status-20230101T010101.json
│   ├── restic-check-20230202T020202.log
│   └── restic-backup-20230101T010101.log
├── config
│   ├── profiles.yaml
│   ├── excludes.txt
│   ├── rclone.conf
│   └── password.txt
├── bin
│   ├── restic_0.15.2_linux_arm64
│   ├── rclone_1.63.1_linux_arm64
│   └── resticprofile_0.22.0_linux_arm64

version: "1"

# Schedules (https://www.freedesktop.org/software/systemd/man/systemd.time.html#Calendar%20Events)
{{ $SCHEDULE_RESTIC_BACKUP := "*-*-* 22:00:00" }}       # Daily at 10PM
{{ $SCHEDULE_RESTIC_CHECK := "Sat *-*-* 04:00:00" }}    # Weekly at 4AM on Saturday
{{ $SCHEDULE_SYNC_BACKUP := "Sun *-*-* 21:30:00" }}     # Weekly at 11.30PM on Sunday
{{ $SCHEDULE_POSTGRES_BACKUP := "Fri *-*-* 20:00:00" }} # Weekly at 8PM on Friday

# Directories
{{ $LOCATION_RESTIC_BINARY := "/home/deck/Desktop/.config/restic/bin/restic_0.15.2_linux_arm64" }}
{{ $LOCATION_RESTIC_REPO := "/home/deck/Desktop/restic-repo" }}
{{ $LOCATION_RESTIC_LOG := "/home/deck/Desktop/.config/restic/logs" }}
{{ $LOCATION_RESTIC_STATUS := "/home/deck/Desktop/.config/restic/logs/statuses" }}
{{ $LOCATION_RESTIC_BLOCKED_FILE := "/home/deck/Desktop/.config/restic/BLOCKED" }}
{{ $LOCATION_RCLONE_BINARY := "/home/deck/Desktop/.config/restic/bin/rclone_1.63.1_linux_arm64" }}
{{ $LOCATION_RCLONE_REPO := "bucket:restic-backup-12345" }}
{{ $LOCATION_RCLONE_CONFIG := "/home/deck/Desktop/.config/restic/config/rclone.conf" }}
{{ $LOCATION_RESTICPROFILE_LOCK := "/tmp/resticprofile-default.lock" }}
{{ $LOCATION_POSTGRES_DUMP := "/home/deck/Desktop/dumps" }}
{{ $LOCATION_PRIMARY_BACKUP_SOURCE := "/home/deck/Desktop/" }}

# Configs
{{ $CONFIG_CURRENT_TIME := .Now.Format "20060102T150405" }}
{{ $CONFIG_RESTIC_PASSWORD := "/home/deck/Desktop/.config/restic/config/password.txt" }}
{{ $CONFIG_RESTIC_EXCLUDE := "/home/deck/Desktop/.config/restic/excludes.txt" }}

global:
  default-command: snapshots                      # Run 'snapshots' when no command is specified
  initialize: false                               # Do not initialize a repository if none exists
  priority: low                                   # Use priority class on Windows and "nice" on Unixes
  min-memory: 100                                 # Minimum required RAM for Resticprofile to start
  restic-lock-retry-after: 5m                     # Retry failed restic command acquisition every 5 minutes
  restic-stale-lock-age: 10h                      # Unlock stale lock if age exceeds 10 hours
  restic-binary: '{{ $LOCATION_RESTIC_BINARY }}'  # Location of the Restic binary

default:
  lock: '{{ $LOCATION_RESTICPROFILE_LOCK }}'      # Local lockfile to prevent concurrent profile runs
  force-inactive-lock: true                       # Detect and remove stale locks
  initialize: true                                # Initialize repository if it doesn't exist
  repository: '{{ $LOCATION_RESTIC_REPO }}'       # Path to Restic repository
  password-file: '{{ $CONFIG_RESTIC_PASSWORD }}'  # File containing repository password
  status-file: '{{ $LOCATION_RESTIC_STATUS }}/{{ $CONFIG_CURRENT_TIME }}-restic-status.json'  # Output status file
  compression: 'max'                              # Maximum compression level
  run-after-fail:                                 # Block syncing if there was a failure. TODO: Add an email
    - 'echo "The command ${PROFILE_COMMAND} has failed in ${PROFILE_NAME}. Please check the logs." > {{ $LOCATION_RESTIC_BLOCKED_FILE }}'

  backup:
    run-before:                                   # Bring down Docker before backup
      - 'systemctl stop docker.socket'
      - 'systemctl stop docker'
    run-finally:
      - 'grep --invert-match -E "^unchanged|\(0 B added, 0 B stored\)|\(0 B added\)" {{ tempFile "backup.log" }} > {{ $LOCATION_RESTIC_LOG }}/{{ $CONFIG_CURRENT_TIME }}-restic-backup.log'  # Copy log file, stripping out any unchanced files
      - 'systemctl start docker'                  # Bring Docker back online after backup
    one-file-system: false                        # Exclude other file systems
    no-error-on-warning: true                     # Don't consider warnings as backup failures
    source:                                       # Directories to back up
      - '{{ $LOCATION_PRIMARY_BACKUP_SOURCE }}'
    exclude-file: '{{ $CONFIG_RESTIC_EXCLUDE }}'  # File containing exclude patterns
    exclude-caches: true                          # Exclude cache files
    schedule: '{{ $SCHEDULE_RESTIC_BACKUP }}'     # Backup schedule
    schedule-permission: system                   # Schedule permission
    schedule-lock-wait: 10m                       # Wait time for the lock during schedule
    schedule-log: '{{ tempFile "backup.log" }}'   # Log file to /tmp. This contains all information, including unchanged files which we do not care about
    verbose: 2                                    # Log details about processed files

  check:
    schedule: '{{ $SCHEDULE_RESTIC_CHECK }}'      # Verification schedule
    schedule-permission: system                   # Schedule permission
    schedule-lock-wait: 10m                       # Wait time for the lock during schedule
    schedule-log: '{{ $LOCATION_RESTIC_LOG }}/{{ $CONFIG_CURRENT_TIME }}-restic-check.log'  # Log file
    read-data: true                               # Verify data during check

  prune:
    dry-run: true                                 # Only prune if safe to do so, change manually
    repack-uncompressed: true                     # Repack all uncompressed data

  forget:
    dry-run: true                                 # Only forget if safe to do so, change manually

  rewrite:
    dry-run: true                                 # Only rewrite if safe to do so, change manually
    forget: true                                  # Remove original snapshots after creating new ones
    exclude-file: '{{ $CONFIG_RESTIC_EXCLUDE }}'  # File containing exclude patterns

  mount:
    allow-other: true                             # Allow other users to access the mount point

  rebuild-index:
    read-all-packs: true                          # Read all pack files to generate new index from scratch

# The following shell profiles are simply to run other shell scripts at a scheduled time
# We do not actually run the primary Restic commands listed, as we exit the process early

shell-postgres:                                   # Profile to run shell scripts only. We exit the current process before Restic can run.
  backup:
    schedule: '{{ $SCHEDULE_POSTGRES_BACKUP }}'   # Postgres backup schedule
    schedule-permission: system                   # Schedule permission
    schedule-lock-mode: ignore                    # Ignore locks, if any
    schedule-log: '{{ $LOCATION_RESTIC_LOG }}/{{ $CONFIG_CURRENT_TIME }}-postgres-backup.log'  # Log file
    dry-run: true                                 # Don't write data
    run-before:                                   # Dump postgres databases
      - 'chmod 777 /var/run/docker.sock'
      - 'docker exec -t immich-postgres pg_dumpall -c -U postgres | gzip > "{{ $LOCATION_POSTGRES_DUMP }}/immich-dump-{{ $CONFIG_CURRENT_TIME }}.sql.gz" && echo "Dumped Immich database: {{ $LOCATION_POSTGRES_DUMP }}/immich-dump-{{ $CONFIG_CURRENT_TIME }}.sql.gz"'
      - 'docker exec -t joplin-postgres pg_dumpall -c -U joplin | gzip > "{{ $LOCATION_POSTGRES_DUMP }}/joplin-dump-{{ $CONFIG_CURRENT_TIME }}.sql.gz" && echo "Dumped Joplin database: {{ $LOCATION_POSTGRES_DUMP }}/joplin-dump-{{ $CONFIG_CURRENT_TIME }}.sql.gz"'
      - 'kill $$'

shell-sync:
  backup:
    schedule: '{{ $SCHEDULE_SYNC_BACKUP }}'       # Sync backup schedule
    schedule-permission: system                   # Schedule permission
    schedule-lock-mode: ignore                    # Ignore locks, if any
    schedule-log: '{{ $LOCATION_RESTIC_LOG }}/{{ $CONFIG_CURRENT_TIME }}-rsync-backup.log'  # Log file
    dry-run: true                                 # Don't write data
    run-before:                                   # Sync the Restic repo, after checking if the repository is in good health
      - 'if [ -f "{{ $LOCATION_RESTIC_BLOCKED_FILE }}" ]; then echo "There has been a problem with the Restic repository, please check the logs. If everything is okay, delete the BLOCKED file." && kill $$; fi'
      - '{{ $LOCATION_RCLONE_BINARY }} -v sync {{ $LOCATION_RESTIC_REPO }} {{ $LOCATION_RCLONE_REPO }} --config={{ $LOCATION_RCLONE_CONFIG }} --b2-hard-delete'
      - '{{ $LOCATION_RCLONE_BINARY }} cleanup {{ $LOCATION_RESTIC_REPO }} --config={{ $LOCATION_RCLONE_CONFIG }}'
      - 'kill $$'

Resticprofile doesn't let me run other shell commands on a schedule, and because I wanted everything in a single configuration, I just created two new profiles which call the backup command. I then made the shell commands run before Restic, and then finally killed the instance before it got to actually run, which effectively does what I needed.