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What non-FOSS software have you been unable to quit?
(beehaw.org)
If it's free and open source and it's also software, it can be discussed here. Subcommunity of Technology.
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Rhino for CAD.
However, I have been using OpenSCAD for parametric design more than the Grasshopper extension.
Thankfully, skipped ArcGIS entirely for QGIS and Python GDAL wrappers.