104
submitted 7 months ago by ylai@lemmy.ml to c/nottheonion@lemmy.world
you are viewing a single comment's thread
view the rest of the comments
[-] ylai@lemmy.ml 28 points 7 months ago* (last edited 7 months ago)

He was criticized also because the girls were not in danger of becoming infected. See e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724388/ :

The Chinese episode has also generated other issues. Several notes demonstrate that this was an experiment and not a therapeutic intervention (even He Jiankui called it a 'clinical trial'). The babies were not at risk of being born with HIV, given that sperm washing had been used so that only non-infected genetic material was used. Further, even though one of the parents (or both) was infected, it did not mean the children were more prone to becoming infected. The risk of becoming infected by the parents' virus was very low (Cowgill et al., 2008). In sum, there was no curative purpose, nor even the intention to prevent a pressing risk. Finally, the interventions were different for each twin. In one case, the two copies of CCR5 were modified, whereas in the other only one copy was modified. This meant that one twin could still become infected, although the evolution of the disease would probably be slower. The purpose of the scientific team was apparently to monitor the evolution of both babies and the differences in how they reacted to their different genetic modifications. This note also raised the issue of parents' informed consent regarding human experimentation, which follows a much stricter regimen than consent for therapeutic procedures.

Other critical articles (e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524470/) have also cited in particular https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779710/, which states in the result section:

No HIV transmission occurred in 11,585 cycles of assisted reproduction using washed semen among 3,994 women (95% confidence interval [CI] = 0–0.0001). Among the subset of HIV-infected men without plasma viral suppression at the time of semen washing, no HIV seroconversions occurred among 1,023 women following 2,863 cycles of assisted reproduction using washed semen (95%CI= 0–0.0006). Studies that measured HIV transmission to infants reported no cases of vertical transmission (0/1,026, 95% CI= 0–0.0029). Overall, 56.3% (2,357/4,184, 95%CI=54.8%–57.8%) of couples achieved a clinical pregnancy using washed semen.

[-] molten@lemmy.world 6 points 7 months ago

Good info. You're absolutely right.

this post was submitted on 01 Apr 2024
104 points (94.8% liked)

Not The Onion

12311 readers
343 users here now

Welcome

We're not The Onion! Not affiliated with them in any way! Not operated by them in any way! All the news here is real!

The Rules

Posts must be:

  1. Links to news stories from...
  2. ...credible sources, with...
  3. ...their original headlines, that...
  4. ...would make people who see the headline think, “That has got to be a story from The Onion, America’s Finest News Source.”

Comments must abide by the server rules for Lemmy.world and generally abstain from trollish, bigoted, or otherwise disruptive behavior that makes this community less fun for everyone.

And that’s basically it!

founded 1 year ago
MODERATORS