Yes! For me that has happened a few major times i can remember. I used to be a huge apple fanboy, until i learned i prefer android and linux way more. i know that's kind of a lame example but it was the first time i became aware of what you're talking about and opened the door to me thinking critically about other things - namely religion and ethics. The other two major times i've had this feeling was with religion, realizing it's not true and leaving the church, and then after that having to think about ethics for myself and realizing there's no good reason to exclude nonhuman animals from moral consideration. That exploiting and abusing them for taste pleasure and fashion and tools was totally unjustifiable.

It's definitely a bizarre feeling, but it's very important to be open to it and stay on the lookout for other things one could be wrong about