First guy is saying, "there's no point in trying to figure out the "answer to the universe", it's a lot easier to be happy if you just go with the flow".

This leads the reader to assume that he's got it all figured out and is a relatively happy guy, an assumption that is subverted when asked plainly, "are you happy?"

I don't know that there's a specific take away here, so much as it just being a funny quip in a larger exchange.