No, it is meme about people finding the unexpected popup they don't understand about something they are not aware of to be annoying. There are a lot of options in windows that don't have anything to do with disabilities that have similar popups which are also unexpected and annoying, this one just happens a lot for certain types of games.

Doubling down by making it about race too is comical. Do you think non-white people in the same situation don't find the meme relatable?