That would require every player even new ones to make very complex loot filters and understand what loot is valuable and not to automate it.

No, it wouldn't, because it would not be mandatory (just like loot filters themselves aren't).

Every item in PoE that is automatically picked up doesn’t take up inventory space (Metamorph organs, Expedition fragments, Sulphite, Azurite).

You're this close to getting it. The extremely limited inventory space in PoE and other ARPGs is a severe design defect, the games would be much better if inventory space was simply infinite. I've had a long and complex discussion about this very topic with someone just a day or two ago, so I don't feel like explaining myself on this point all over again. Feel free to check that if you're interested.

It also feeds into the dopamine loop, when you get an exciting drop you see it on the ground it doesn’t automatically just get sucked into your inventory.

That would be much better solved by having a pop-up show you the exciting drop as you automatically pick it up. That way the player would still get their dopamine hit without the game also constantly filling their annoyance meter by making them pick up garbage manually.